Acetonitrile, for UHPLC, suitable for mass spectrometry (MS)

Linear Formula: CH3CN:
CAS # 75-05-8
Molecular Weight: 41.05
Beilstein No: 741857
Synonym(s): ACN, Cyanomethane, Ethyl nitrile, Methyl cyanide

Grade: HPLC Grade
Assay: ≥99.92%
Technique(s): HPMass Spectrometry (MS) suitable
Applications: PFAS Testing
bp: 81-82 °C (lit.)
Vapor Pressure: 72.8 mmHg ( 20 °C)

General description
Acetonitrile, an aliphatic nitrile, is a highly volatile, aprotic polar organic solvent that finds wide use in analytical determinations. It is UV-transparent − a property that facilitates its utilization in spectrophotometric and fluorometric analyses. Its low viscosity, high elution strength and miscibility in water makes it viable in many chromatography systems.
Its other applications include its use as a mobile phase additive and as an extraction solvent in liquid-liquid extraction (LLC), solid-phase extraction (SPE) and microextraction for chromatographic applications, etc.[1]
Application
Acetonitrile may be used:

• As an extraction solvent for the quantification of pesticide analytes in foodstuffs[2][3] and tea,[4] industrial dyes in juice and wine[5] by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS).
• As an organic modifier in the determination of bisphenol A-diglycidyl ether, bisphenol F-diglycidyl ether and their derivatives in canned food and beverages by fast LC–MS/MS.[6]

Acetonitrile, an organic solvent, is used as a mobile phase/extraction solvent in the ultra-high performance liquid chromatography − tandem mass spectrometry (UHPLC-MS) analysis of pesticides in tobacco samples.[7] It can be potentially used with a reverse-phase column to determine the concentration of diclofenac (DCF).[8]

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