(±)-Methadone is a synthetic opioid analgesic used clinically for pain management and maintenance therapy in opioid dependence. This certified reference material (CRM) is supplied as a single-component solution at 1 mg/mL in methanol and is intended for analytical calibration, method validation, and quality control testing.

This standard is suitable for gas chromatography (GC), liquid chromatography (LC), and mass spectrometry–based methods including GC/MS and LC/MS/MS. It is commonly used in forensic toxicology, clinical toxicology, pharmaceutical research, and prescription monitoring applications to ensure accurate identification and quantification of methadone in biological and environmental samples.

Each unit is packaged in a sealed ampule to preserve concentration integrity and minimize contamination risk. Certified reference materials are produced under stringent quality systems, with lot-specific documentation provided in the certificate of analysis.

Shipping and Storage Notice
Please note that shipping and long-term storage conditions for certified reference materials may differ. Manufacturers determine the most appropriate shipping method based on product stability and shipping data. Some CRM standards may ship at ambient temperature even though recommended long-term storage conditions are refrigerated or frozen. This does not affect product integrity when handled according to manufacturer documentation.