TWEEN® 80 skeletal structure

TWEEN® 80, BioXtra, 500 mL

SKU: P8074-500ML
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TWEEN® 80, 500 mL

BioXtra, viscous liquid

Synonym(s):
TWEEN® 80, POE (20) sorbitan monooleate, Polyethylene glycol sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polysorbate 80

Key Documents
CAS Number: 9005-65-6
MDL Number: MFCD00082107
UNSPSC Code: 12161900
NACRES: NA 21

General description
["TWEEN"] 80 is a polyethylene sorbitol ester, broadly used in biochemical applications like solubilizing proteins, isolating nuclei from cells in culture, and growing tubercle bacilli. It is also useful in emulsifying and dispersing substances in medicinal and food products. TWEEN 80 acts as an active drying agent in ice cream.
Application
["TWEEN"] 80 has been used:

• to dissolve rapamycin (RAPA) for immunosuppressive treatment to perform in vivo studies in mice
• to dissolve remodelin and remodelin Fluor to assess remodelin toxicity in vivo and small molecule dosing
• to prepare assay medium for the microbiological assay for total folate

Legal Information
TWEEN is a registered trademark of Croda International PLC

BioXtra-grade polysorbate 80 for biochemical and pharmaceutical use. Supports protein solubilization, in vivo small molecule delivery, and folate microbiological assays. CAS 9005-65-6. Viscous liquid.

Properties:

Description: Non-ionic
Quality Level: 200
Product line: BioXtra
Form: Viscous Liquid
Mol Wt:
-micellar avg mol wt 79,000
-average mol wt 1310
Composition: Oleic acid, ≥58.0% (balance primarily linoleic, palmitic, and stearic acids)
Aggregation Number: 60
Techniques:
-DNA extraction: suitable
-RNA extraction: suitable
-cell culture | mammalian: suitable
-protein purification: suitable
Impurities: ≤0.025% Phosphorus (P)
Ign residue: <0.1%
CMC: 0.012 mM (20-25°C)
Transition Temp:Ccloud point 65 °C
Density:
-1.06 g/mL at 25 °C (lit.)
Anion traces:
-chloride (Cl-): <0.05%
-sulfate (SO42-): <0.05%
Cation traces:
-Al: <0.0005%
-Ca: <0.001%
-Cu: <0.0005%
-Fe: <0.0005%
-K: <0.005%
-Mg: <0.0005%
-NH4+: <0.05%
-Na: <0.05%
-Pb: <0.001%
-Zn: <0.0005%
HLB 15
SMILES string: CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO

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