Chlorotrimethylsilane (TMCS), ≥98.0% (GC) - 250mL

SKU: 92361-250ML
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Chlorotrimethylsilane (TMCS) is a reactive organosilane reagent supplied at ≥98.0% purity (GC). It is widely used as a silylating agent in organic synthesis and analytical sample preparation. TMCS is commonly employed for the protection of alcohols, formation of trimethylsilyl derivatives, and silanization of glassware and surfaces to create hydrophobic coatings.

This reagent is suitable for derivatization workflows, surface modification, and moisture-sensitive reaction chemistry in research and analytical laboratories.

Chemical Name: Chlorotrimethylsilane
Synonyms: TMCS; Trimethylchlorosilane; Trimethylsilyl chloride
Linear Formula: (CH₃)₃SiCl
CAS Number: 75-77-4
Molecular Weight: 108.64 g/mol
Assay: ≥98.0% (GC)
Form: Liquid
EC Number: 200-900-5
MDL Number: MFCD00000502
NACRES: NA.22
PubChem ID: 57653472

Specifications

Chlorotrimethylsilane, ≥98.0% (GC)

• Assay: ≥98.0% (GC)
• Form: Liquid
• Boiling Point: 57 °C (lit.)
• Melting Point: −40 °C (lit.)
• Density: 0.856 g/mL at 25 °C (lit.)
• Refractive Index: n20/D 1.387 (lit.)
• Vapor Pressure: 100 mmHg at 25 °C
• Vapor Density: 3.7 (vs air)
• Autoignition Temperature: 752 °F
• Explosive Limit: 6.4%
• Quality Level: 200

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